Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2012.0246


Personalized medicine through genome science and network biology advances.

William CS CHO, MD, PhD.

Affiliation: William CS Cho, Scientific Officer, Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13/F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong.


Most human chronic diseases arise from dynamic complex interactions at the molecular level as well at whole organism-environment cooperation. High-throughput next-generation sequencing coupled with modern microarrays provides now a comprehensive genome landscape including structural and functional integrated analysis. With advances in network biology and predictive networks models a highly complex dynamic network of a person is evaluated considering his/her inherited genomic background, lifestyle and cooperation in ecosystem with aim to predict current and future risk of disease and in patients with established disease to tailor the optimal treatment.

(Citation: Gastric & Breast Cancer 2012; 11(4): 216-220)



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last update: 30 October 2012