Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2011.0163


Family history and BRCA testing change surgery for breast cancer in the USA.

Eleftheria Ignatiadou, M.D. and Charalabos Batsis, M.D.

Affiliation: Dr. Eleftheria Ignatiadou, and Charalabos Batsis, Assistant Professor of Surgery, Department of Surgery, University Hospital of Ioannina, Ioannina, TK 45110, Greece.


Since there is no abstract available we provide the first paragraph.

Family history and young age at diagnosis of unilateral breast cancer are thought to be risk factors for contralateral breast cancer after unilateral breast cancer surgical treatment. This fact has resulted in a dramatic increase by 150% of bilateral mastectomy among young women and those with family history with unilateral breast cancer diagnosis in the USA [1]. However, this prophylactic contralateral mastectomy suggests an overtreatment for many of these women. The recent wider availability of genetic testing in the USA may allow a more targeted surgery for women with unilateral breast cancer and an increased risk of a new primary contralateral breast tumor.

(Citation: Gastric & Breast Cancer 2011; 10 (2): 97-99)

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last update: 15 March 2011