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Recurrence is the cause of treatment failure that leads to death cancer patients. The ultimate goal of current and future biomedical research is how to understand and develop effective drugs to overcome molecular mechanisms underlying cancer recurrence [1, 2]. Despite complete tumor resection (R0) and adjuvant chemotherapy, radiotherapy and targeted therapy, recurrence rates in patients with stages II/III solid cancer still remain high suggesting that cancer is a highly complex, heterogeneous and incurable disease [3]. Evidence suggests that laparoscopic surgery improves postoperative short-term outcomes and quality-of-life (QOL) without any negative effect on oncological outcomes of patients with colon cancer but the impact of this minimally invasive approach on recurrence risk for gastric, rectal and other solid cancer is still unclear [4-10].

(Citation: Gastric & Breast Cancer 2011; 10(3): 173-175)

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