Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2011.0194


Sigmoid or rectal cancer: do patients benefit from high ligation of inferior mesenteric artery ?

Ernst Hanisch, MD.

Affiliation: Prof. Ernst Hanisch, Chefarzt und Ärztlicher Direktor, Klinik für Allgemein- Viszeral- und Endokrine Chirurgie, Asklepios Klinik Langen, Akademisches Lehrkrankenhaus der JWG-Universität Frankfurt, Röntgenstr 20, 63225 Langen .

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Since there is no abstract available we provide the first paragraph

The extent of lymph node dissection in the surgical treatment of primary left colon or rectal cancer is debated. A latest well designed and appropriately conducted phase 3 randomized trial has provided disappointing results on cetuximab treatment for KRAS wild-type colorectal cancer. Therefore, the interest in achieving the best possible locoregional tumor control by surgery re-attracts major interest by physicians and treatment. In many specialized institutions high ligation of inferior mesenteric artery has been standardized as a surgical procedure with no increase in operating time and postoperative morbidity. But evidence for reducing local and nodal recurrence after this surgical approach is still insufficient. Here, I discuss whether patients with sigmoid or rectal cancer benefit or not from high ligation of inferior mesenteric artery and splenic flexure mobilization.

(Citation: Gastric & Breast Cancer 2011; 10(4) 241-243)

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Online ISSN : 1109 - 7647
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last update: 9 September 2011