Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2017.0262


RNA-sequencing identifies a new molecular classification of pancreatic cancer: Implications and challenges.

Dimitrios K. Christodoulou, MD, PhD.

Affiliation: Dimitrios K. Christodoulou, (DKC), Professor of Gastrentorolgy, Department of Gastroenterology, Ioannina University Hospital, Ioannina, TK 45110, Greece.


Prognosis of pancreatic ductal adenocarcinoma (PDA) remains grim. Advances and standardization of complete tumor resection (R0) and adjuvant chemotherapy have led to a 30-50% 5-year survival for patients with resectable, early-stage disease (T1N0). However, survival rates for more advanced stages are poor. The advent of next-generation sequencing (NGS) technologies a decade ago has revolutionized biomedical research. More recently, efforts are focused on how to translate the tremendous potential of NGS on the analysis of clinical cancer genome on patient-derived samples into clinical care.

(Citation: Gastric & Breast Cancer 2017; 12(2): 79-84)

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Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655

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last update: 31 August 2017