Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2019.0285


Spatiotemporal genome and transcriptome analyses enhances the development of new therapeutic targets for solid tumors.

Prof. Dr. A. Sendler MD, PhD.


Although the development and approval of targeted drugs for metastatic tumors is rapidly increasing the establishment of these agents, with a few exceptions, has failed in the adjuvant or neo-adjuvant setting. The discovery of valid cancer driver genes and druggable mutations through recent recommendations on genomic and transcriptomic studies as well as clinical trials realized the necessity to overcome the recent evidence of interpatient and intrapatient for genetic, genomic and transcriptional heterogeneity. This review discusses the potential and challenges to improve the current poor oncological outcomes of major cancer types.

(Citation: Gastric & Breast Cancer 2019; 14(1): 73-82)



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last update: 10 June 2019