Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2019.0286


Single-cell genome and transcriptome sequencing and editing technologies enhance understanding of regulatory networks with future clinical implications for breast cancer.

Prof. G. Zografos, MD, PhD.


Rapid progress from bulk NGS to breakthrough combination of single-cell RNA-sequencing and CRISPR-CAS9 system is revolutionizing biomedical research in health.
Particularly in cancer, initial data demonstrate cell-to-cell heterogeneity dependence drug sensitivity represent the most great hope for revolutionizing precision oncology. Moreover, the CRISPR-CAS9 system provides high expectation for the discovery of novel therapeutic targets. The breakthrough of both techniques represents an exciting distant future perspective to breast cancer precision medicine.

(Citation: Gastric & Breast Cancer 2019; 14(1): 83-90)



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last update: 10 June 2019