Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2019.0287

PERSPECTIVE

Exploring functional Non-coding mutations for understanding regulatory networks and clinical implications for cancer.

W. CS CHO, MD, PhD.

 

Abstract
The validity of Whole-exome sequencing (WES), Whole-genome sequencing (WGS) and RNA-sequencing in the exploration  of primary tumor and circulating cell-free DNA NGS (cfDNA-NGS) for the identification of intratumor heterogeneity (ITH) and cfDNA-NGS-based genetic, genomic and transcriptional heterogeneity represents major hope for overcoming drug resistance, and relapse rates leading to improved overall survival.

(Citation: Gastric & Breast Cancer 2019; 14(1): 94-109)

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Online ISSN : 1109 - 7647
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last update: 10 June 2019