Highly promising data on genome and transcriptome bulk sequencing-based have recently been reported in top journals. However, validation is required concerning the lack of protocols and appropriate large-scale studies.
This perspective article proposes a step-wise algorithmic approach to translate genomic and transcriptomics into initial phase of clinical precision oncology. Moreover, in this perspective article, potential clinical implication of non-coding genome functionality and transcriptional networks are discussed.
(Citation: Gastric & Breast Cancer 2019; 14(1): 110-117)