Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2021.0303

Original Article

Application of Optosonographic Surgical Monitoring for the Diagnosis of Various Pathologies.

Zoltan M. SIGAL, Olga V. SURNINA, Olga A. SIGAL, Fedor G. BABUSHKIN, Konstantin E. ZOLOTAREV, Sophia Z. SIGAL.

Affiliation:
1Federal State Budgetary Educational Institution of Higher Education, Izhevsk State Medical Academy, Russian Federation Ministries of Health, Kommunarov Street, 281, 426034, Izhevsk, Russia.
2Budgetary Institution of Health Care of the Udmurt Republic, Republican Clinical and Diagnostic Center, Ministry of Health of the Udmurt Republic, Izhevsk, Russia.

E-mail:surnina.ima@bk.ru

Abstract
Background
False-negative and false-positive diagnostic results might lead to long-term psychosocial consequences, unnecessary surgery or death. Developing a high-sensitive and rapid diagnostic method is urgent.
Objective
This research presents the results of application of optosonographic monitoring for the diagnostics of various pathologies, by numerical indicators of local hemodynamics and non-pulse optical density of tissue.
Methods
A control group (n=200) of healthy people and an observation group (thyroid disease n= 632, breast disease n=732 and bowel obstruction n=1400) were examined. ROC curve analysis was performed to determine the sensitivity, specificity and accuracy of the proposed method.
Results
Specificity and accuracy of pulse and non-pulse optical density in breast pathology examination showed highest results (96% and 96.6%; 97.9% and 94.6 respectively). Non-pulse optical density diagnostic method has shown excellent predictive capabilities in thyroid cancer diagnosis (AUC = 0.955). Ultrasound and histological analysis confirmed the predictive capabilities of this method in the diagnosis of intestinal viability.
Findings
Based on results it can be concluded that optosonographic monitoring is one of the most informative diagnostic methods.
Implications: To study the possibility of this method as broad-spectrum diagnostic tool.
Contribution: Continuing work on this hot topic, will contribute to improving the diagnosis of pathologies.

Keywords: optosonographic monitoring; optical density; thyroid gland; breast; bowel obstruction.

(Citation: Gastric & Breast Cancer 2021; 16(1): 24-35)

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last update: 1 January 2021