Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2021.0305


Discovery of novel drugs and biomarkers drive breakthrough matched combinatorial therapy.

William CS CHO, MD, PhD.


Next Generation Sequencing (NGS) and CRISPR -Cas technologies are transforming biomedical research towards Precision Medicine [1-3]
Particularly in cancer, an explosion in genome and transcriptome analysis has not only created a revolutionary roadmap but also is initiating to guide Precision Oncology [4] .
The potential and challenges of whole genome and transcriptome analysis in time and space by developing and validating novel prediction biomarkers and novel targeted drugs[5, 6] are described. Moreover, combination drug therapy matched the individual patients set of actionable mutations [7] are discussed Optimal individualized meaningful treatment is also discussed in this review.

(Citation: Gastric & Breast Cancer 2021; 16(1): 46-55)



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last update: 1 January 2021