Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2021.0306

Mini-Review

From Inexact to Cancer Precision Medicine.

Chee-Seng Ku, MD, PhD.

 

Abstract
The estimates on cancer incidence, late diagnosis and mortality rates currently and for 2030 are disappointing, suggesting a remarkably limitations of current conventional research to manage and control this complex disease [1, 2]. To overcome these pessimistic figures the transition from current inexact biomedical research to whole genome, transcriptome and interactome analysis with sequencing, editing and interaction network mapping appear essential [3-7]. Latest achievements in understanding tumorigenesis, dynamic cancer genome evolution and progress to early tumor formation is essential for the development of clinical primary prevention [[8], Mechanisms generating cancer genome complexity from a single cell division error.

Moreover, the development of novel screening tools via liquid biopsy-based cfDNA-NGS is described [9]. Furthermore, the optimization of individualized therapy through the creation of a Drug bank coupled with predictive biomarkers are also highlighted [10].

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(Citation: Gastric & Breast Cancer 2021; 16(1): 56-63)

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Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655

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last update: 1 January 2021