Abstract:

Gastric cancer is one of the commonest cancers worldwide . The management of early-stage gastric adenocarcinoma is complex , and surgical resection remains the primary curative treatment. The most commonly performed operations for gastric cancer are total and subtotal gastrectomy, depending on the location of the tumour and the ability to gain adequate tumour free margins. Despite the surgery, the overall survival remains poor. At present there is proven benefit of both perioperative chemotherapy with epirubicin/cisplatin/fluorouracil (ECF) and postoperative chemo-radiotherapy (McDonald regimen). Other regimens of perioperative chemotherapy and preoperative chemo-radiotherapy are under investigation .

Keywords: Gastric adenocarcinoma, ECF, Gastrectomy, D2, Chemoradiotherapy.