Personal genomics represent the most rational scientific way to achieve the goal of the century: Personalized medicine. Three more entirely sequenced genomes are here. The first one was for a cancer patient, the other first one was for an Asian and the last first one was for an African individual. These three whole-genome sequencing together with an accompanied Editorial and several selection opinion articles have been published in the Nov. 6, 2008 issue of Nature [1, 2].