Current
best practices and rationalistic perspectives in causation-based
prevention, early detection and multidisciplinary treatment
of breast and gastric cancer
Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2009.0099
News & Views
Personal Genetics and impact on breast surgeon
George Zografos M.D, and Ioannis Georgiou PhD
Affiliation:
From the Breast Unit, (GZ) 1st Department of Propaedeutic Surgery, University of Athens, Greece and (IG), from the Laboratory of Human Reproductive Genetics, Department of Obstetrics and Gynaecology, Medical School, University of Ioannina, Ioannina, Greece
Since there is no abstract available we provide the first paragraph
New generation DNA sequencing and microarray technologies have revolutionized basic-science research directions. Instead conventional research focus on a single gene, the new technologies shape now a novel roadmap for understanding the complex causative cancer network. Cancer genetics with the identification of BRCA1 and BRCA2 genes and the currently widely used genetic testing already influence surgeon's decisions in both the prevention and treatment setting.
How rapid advances in personal genomics, quantitative genetics and systems biology may also affect breast cancer surgical practice in the next years come?
Current technology enables the collection of multiple genetic and genomic data. However, it remains a major challenge how to interpret all this vast majority of data.
You can have an online full-text access and a PDF of this article:
Either purchase this paper for €33 EUR. Please, click here
