Since there is no abstract we provide the first sentence
The basic surgical oncology principle of complete removal of the primary tumor (R0 resection) for nearly all solid tumors has been debated. for the treatment of early-stage breast cancer Based on the ?systemic? view of breast cancer and the clinical data of the NSABP B-08 trial [1] and the emphasis on systemic treatment for improving overall survival [2], it has been suggested that local control during breast-conserving therapy (BCT) was of limited value with regard to overall survival. However, such a strategy with little attention on microscopic tumor-free margins during BCT may be is associated with increased risks not only of local recurrence but also and most important mortality [3, 4]. panerai replica
