Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2006.0047


Deciding on genetic testing for hereditary colorectal cancer (lynch): Is the new schotisch model clinically applicable?
Dimitrios Christodoulou, Michael Fatouros, Theodore Liakakos, Dimitrios H. Roukos, Angelos M. Kappas and Epameinondas Tsianos.
Since this article has no abstract we provide the first paragraph

One million people are struck annually from colorectal cancer worldwide [1] and 150,000 of these come from the United States [2]. Although hereditary nonpolyposis colorectal cancer (HNPCC), also called Lynch syndrome [3], accounts for only 2-4% of all colorectal cancer cases [4,5], the high incidence of colorectal cancer, being the third most common malignancy, has stimulated research about HNPCC. The different prevention strategy and the role of early detection and treatment of sporadic and hereditary colorectal cancer underline the importance of identification of mutation carriers of HNPCC, either in healthy individuals or in patients [6].

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Online ISSN : 1109 - 7647
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last update: 11 December 2006