Gastric
& Breast Cancer e-journal
DOI: 10.2122/gbc.2006.0050
NEWS & VIEWS
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Positive Perioperative (ECF) Chemotherapy Trial for Gastric Cancer: Primary chemotherapy or surgery?
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Evangelos Briasoulis, MD, Theodore Liakakos, MD, Nikolaos Xeropotamos, Dimosthenis Ziogas, MD,
Dimitrios Roukos,* MD, and Michael Fatouros, MD
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The MAGIC trial provides, for a first time in the literature, level I evidence for a survival benefit of a new treatment option. However, the trial was designed to provide overall data for all patients with stage II, IIIA and IIIB and not not stage-specific subgroups survival analysis. Although the study provides robust results, can perioperative chemotherapy replace current standard surgery in the clinical treatment practice of operable gastric cancer?
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