Figure
5 | Receptor tyrosine kinases:sites of
therapeutic intervention.IWC Replica Watches Deregulation of the
receptor tyrosine kinase (RTK) signalling network
is crucial for the development and progression
of hyperproliferative diseases as cancer. Neutralizing
antibodies, which block the bioactivity of RTK
ligands, RTK-targeted antibodies, which either
target overexpressed receptors or receptor heterodimerization,
and small-molecule inhibitors RTK kinase activity
have been developed to interfere with RTK signal
transduction.