Current
best practices and rationalistic perspectives in causation-based
prevention, early detection and multidisciplinary treatment
of breast and gastric cancer
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VIEW
POINT |
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| Gastric
Cancer: Histological Diagnosis and Classification from Classical to Molecular Pathology Anna Batistatou, MD, PhD, Dimitrios Stefanou, MD, and Niki J. Agnantis, MD, PhD |
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Abstract |
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| Gastric
cancer is one of the most common causes of cancer-related deaths,
despite its decreasing incidence. Rapid progress has been achieved
in recent years in elucidating tumorigenesis and a multifactorial
model of human gastric carcinogenesis is currently accepted. It
is now evident that the critical genetic alterations are different
in diffuse and intestinal type gastric cancer. Moreover, the role
of E-cadherin gene alterations is elucidated in sporadic as well
as in hereditary diffuse gastric cancer. In the present review
recent advances in molecular Pathology of gastric cancer are discussed..
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