Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

 

EDITOR - IN - CHIEF

Professor Dimitrios H. Roukos, MD, PhD

Surgery & Precision Cancer Genome Medicine

Founding Director:
* Center for Biosystems and Genome Medicine
* Research & Innovation Commission
 
  Ioannina University, School of Medicine
Department of Surgery, University Hospital of Ioannina
Biomedical Research Foundation Academy of Athens (BRFAA)
* Systems Biology Unit
 
Publications: 231 papers in PubMed including 80 on clinical cancer genome analysis applying Next - Generation Sequencing, molecular interactions regulatory networks and nonlinear transcriptional biocircuits for clinical implications as well as 30 on Precision Medicine - Oncology.
Citations: 7800 including 13 papers each with > 100 citations; h-index 69 (Scopus)  

Phones: +30 265100-5572/-7423 (Univ.); +302651099-695/-769 (Univ. Hospital)
E-mail: droukos@uoi.gr
            Website: www.gastricbreastcancer.com

 
Biosketch profile  
SHORT CV
Dr. D. Roukos has graduated from Athens University School of Medicine, Greece. He underwent specialist training in surgery at the J.W.Goethe-University Hospital in Frankfurt a.M., Germany where received his Doctorate (Dr.med). He moved back to Greece and since 1990 works at the Ioannina University School of Medicine.

Stepwise progress from Clinical Research to Precision Oncology

1985 – 2000

LINEAR EXPERIMENTATION: Focus on traditional Surgical Oncology

2001 – Today

Translational single – gene research, prevention of hereditary cancer syndromes (Breast, Colorectal, Gastric); targeted therapy

2007 – Today

NONLINEAR EXPERIMENTATION: Molecular interaction networks, Genotype – Phenotype map

2008 – 2011

Genome-Wide Association Studies (GWAS)

2010 – Today

NEXT – GENERATION SEQUENCING (NGS): Conventional single biopsy – based approach

2014 – Today

PRECISION CANCER GENOME MEDICINE
Intrapatient Heterogeneity (IPH): Biomarkers and Drugs Discovery

  • Dynamics of comprehensive IPH (intratumor and circulating subclonal heterogeneity)
  • Linear transcription-based drugs targeting IPH
  • Innovative solutions towards future nonlinear transcription drugs targeting transcriptional biocircuits

National and International assessment, recognition and distinctions

2011 – Today

Evaluator in International Innovative Projects: In EU – EC (FP7; Horizon 2020), France, Italy Ministry of Universities and Research, Belgium.

2012– Today

Founding Director Center for Biosystems and Genome Network Medicine, Ioannina University, Ioannina, Greece.

2014 – Today

Affiliation in BRFAA, Athens, Greece.

2015 – Today

Scientific Director Research & Innovation Commission of Ioannina University, School of Medicine

Editorial Board Member in <20 Journals indexed in PubMed and ISI

Invited Speaker in International Meetings (<100)

Reviewer in International in multiple high-impact Journals including Nat Biotech, Nat Rev Genet, Nat Protocol, Lancet Oncology, Nat Rev Clin Oncol, …

 

 

ISSN : 1109 - 7647
   Print ISSN : 1109 - 7655

 

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.



Search only trustworthy HONcode health websites:

last update: 23 February 2017