Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer
DOI: 10.2122/gbc.2004.0033


Endoscopic Mucosal Resection – A Comprehensive Review

Dimitrios Sigounas, M.D., Dimitrios Christodoulou, M.D., Norman Marcon, M.D., FRCP(C),
Epameinondas V. Tsianos, M.D.

From the department of Hepato-Gastroenterology Unit (DS,DC,EVT), 1st Department of Internal Medicine, Medical School, University of Ioannina – Greece, 2The Centre for Advanced Therapeutic Endoscopy and Endoscopic Oncology, Saint Michael’s Hospital, University of Toronto, Canada(DC,NM)
Correspondence to: Dr Epameinondas V. Tsianos, M.D. Professor of Medicine 1st Department of Internal Medicine Division of Internal Medicine Medical School University of Ioannina – Greece Unversity Campus 45110, Ioannina, Greece Tel: + 30 26510 97501 Fax: + 30 26510 97016 E-mail:

EMR in the Colon and Rectum

Aiming at much better quality of life by similar mortality rates, research has been focused on developing of new techniques. EMR for early – stage esophagus, gastric and colorectal cancers, under strict control of several specific criteria, may replace conventional standard surgical treatment.

It is well recognized that early detection of gastrointestinal cancers is one of the most important factors that improves prognosis in these patients[2]. Newer techniques, such as magnifying endoscopy combined with chromoendoscopy[25,26,76],photodynamic diagnosis[77,78] and light-induced autofluorescence spectroscopy[79], to mention a few, hold promise for earlier detection of malignant lesions.

In the face of these newer implications, EMR emerges as an important new addition to our therapeutic armamentarium. It is expected to play an important role in establishing a diagnosis and treating early GI cancer in the future. Intensive research, newer technical implications and well-scheduled randomized trials, along with the adoption of common, universally-accepted criteria are needed in order to establish EMR as a first-line treatment or at least as a reliable alternative to surgical therapy for patients with early GI cancers.

Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655
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last update: 3 February 2004