Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer
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The GBC e-journal expands scientific topics, beyond Gastric & Breast Cancer to all cancer types, with special interest in Cancer Precision Medicine
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GBC
TOP 10 Cancer Precision Medicine (CPM) papers in 2019
* The selection was based on:
1. Validity of data
2. Innovation
3. Potential fast translation into the clinic.
 
1. Sabarinathan R, Pich O, Martincorena I, et al. The PCAWG Drivers and Functional Interpretation Group and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network. The whole-genome panorama of cancer drivers.
This pre-print on the PCAWG Consortium will be published in Nature, 2020.
 
2. Wan N, Weinberg D, Liu TY, et al. Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA. BMC Cancer. 2019 Aug 23;19(1):832. doi: 10.1186/s12885-019-6003-8.
This is a pre-print in BioRxiv.
 
3. Wang H, Nakamura M, Abbott TR, et al. CRISPR-mediated live imaging of genome editing and transcription. Science. 2019 Sep 20;365(6459):1301-1305. doi: 10.1126/science.aax7852.
 
4. Demircioglu D, Cukuroglu E, Kindermans MA, et al. Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters. Cell. 2019 Sep 5;178(6):1465-1477.e17. doi: 10.1016/j.cell.2019.08.018.
 
5. PCAWG Transcriptome Core Group; Calabrese C, Davidson NR, Fonseca1 NA, et al. Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
This pre-print on the PCAWG Consortium will be published in Nature, 2020.
 
6. Porteus MH. A New Class of Medicines through DNA Editing. N Engl J Med. 2019 Mar 7;380(10):947-959. doi: 10.1056/NEJMra1800729.
 
7. Ligorio M, Sil S, Malagon-Lopez J, Nieman LT, et al. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell. 2019 Jun 27;178(1):160-175.e27. doi: 10.1016/j.cell.2019.05.012.
 
8. Kyrochristos ID, Roukos DH. Comprehensive intra-individual genomic and transcriptional heterogeneity: Evidence-based Colorectal Cancer Precision Medicine. Cancer Treat Rev. 2019 Nov;80:101894. doi: 10.1016/j.ctrv.2019.101894.
 
9. Kyrochristos ID, Ziogas DE, Roukos DH. Dynamic genome and transcriptional network?based biomarkers and drugs: precision in breast cancer therapy. Med Res Rev. 2019 May;39(3):1205-1227. doi: 10.1002/med.21549.
 
10. Kyrochristos ID, Ziogas DE, Roukos DH. Drug resistance: origins, evolution and characterization of genomic clones and the tumor ecosystem to optimize precise individualized therapy. Drug Discov Today. 2019 Jun;24(6):1281-1294. doi: 10.1016/j.drudis.2019.04.008.
GBC

First Issue 2019

 
 
 
 
 
 
 
 
 
 
 
 
 
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Past Issue

 
 
 
 
 
 
 
 
 
Ιατρική Ακριβείας του Καρκίνου
These landmark papers have attracted scientific interest to: point
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Nice, May 30, 31, 3rd International COnference on Women Health and Breast Cancer

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2018

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15. Amsterdam, October 18-19, 14th Global Biomarkers Summit
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20. Helsinki, November 26-27, International Conference on Epigenetics and Epitranscriptomics
21. Rome, November 26-28, World Structural and Molecular Biology Conference

Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655 ..

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last update: 25 December 2019